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@DS3-2024

DS3 2024

Course Materials for Data Science for Diverse Scholars in Down Syndrome Research (DS3) 2024

Morning sessions: Short Read Sequencing Workshop

Website: https://biodatasci.colorado.edu/shortread/

GitHub repository: Dowell-Lab/srworkshop

Afternoon sessions (2-4pm)

Day 1: The Human Trisome Project

Instructor: Matthew Galbraith
An overview of the Human Trisome Project and the journey from data to discovery.

Day 2: Omics and Data Science Concepts

Instructor: Matthew Galbraith
An introduction to important concepts in omics and best practices in data science.

Getting started with R and RStudio
GitHub repository: installing_updating_R-RStudio

Alternatives to running locally:
Posit Cloud
Cavatica

Day 3: Reproducible data analysis using R and RStudio

Instructor: Matthew Galbraith
A guide to conducting reproducible data analysis in R using RStudio and tidy principles.

GitHub repository: tidy_data_exercise

GitHub repository: Rproject_template

Day 4: Linear regression analysis of omics data in R

Instructor: Matthew Galbraith
An introduction to hypothesis testing and analysis of data using linear regression.

GitHub repository: linear_regression_exercise

GitHub repository: HTP_linear_regression_example

Day 5: Analysis of bulk RNAseq data in R

Instructor: Matthew Galbraith
An overview of the high-throughput sequencing analysis workflow, quality control, and bulk RNA-sequencing analysis in R.

GitHub repository: HTP_DESeq2_analysis

Day 6: Visualization and clustering analysis with HTP examples

Instructor: Jim Costello
An overview of data visualization, dimension reduction, and clustering methods leveraging HTP datasets.

GitHub repository: Visualize_Cluster_HTP

Day 7: Supervised Machine Learning with HTP examples

Instructor: Jim Costello
Applications of simple machine learning methods to predict outcomes leveraging HTP datasets.

GitHub repository: PredictiveModels

Day 8: Analysis of mass cytometry data in R

Instructor: Matthew Galbraith
Introduction to high-dimensional single cell analysis using HTP mass cytometry data.

GitHub repository: HTP_beta_regression_example

GitHub repository: mass_cytometry_dataviz

Day 9: Analysis of INCLUDE data with R using Cavatica

Instructor: Matthew Galbraith
A guide to the INCLUDE Data Hub and how to transfer data to the Cavatica platform for analysis.

GitHub repository: R_analysis_CAVATICA

Day 10: Data Analysis with R Continued

Instructor: Matthew Galbraith

Popular repositories Loading

  1. .github .github Public

  2. Getting-started-with-R-and-RStudio Getting-started-with-R-and-RStudio Public

  3. Rproject_template Rproject_template Public

    R

  4. linear_regression_exercise linear_regression_exercise Public

    R

  5. tidy_data_exercise tidy_data_exercise Public

    R

  6. HTP_linear_regression_example HTP_linear_regression_example Public

    R

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