diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index c67210a9d9bb9..71aeabb7a03f0 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -30,7 +30,7 @@ cached-ipaddress==1.0.1
 certifi>=2021.5.30
 ciso8601==2.3.3
 cronsim==2.7
-cryptography==46.0.5
+cryptography==46.0.6
 dbus-fast==3.1.2
 file-read-backwards==2.0.0
 fnv-hash-fast==1.6.0
diff --git a/pyproject.toml b/pyproject.toml
index 647b6f7471114..5a256b7f26c6b 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -61,7 +61,7 @@ dependencies = [
   "lru-dict==1.3.0",
   "PyJWT==2.10.1",
   # PyJWT has loose dependency. We want the latest one.
-  "cryptography==46.0.5",
+  "cryptography==46.0.6",
   "Pillow==12.1.1",
   "propcache==0.4.1",
   "pyOpenSSL==25.3.0",
diff --git a/requirements.txt b/requirements.txt
index ad9464932e716..babe07736ad80 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -22,7 +22,7 @@ bcrypt==5.0.0
 certifi>=2021.5.30
 ciso8601==2.3.3
 cronsim==2.7
-cryptography==46.0.5
+cryptography==46.0.6
 fnv-hash-fast==1.6.0
 ha-ffmpeg==3.2.2
 hass-nabucasa==1.15.0