diff --git a/.github/workflows/cron.yml b/.github/workflows/cron.yml
index a784f2c7fa..b34f2c87ac 100644
--- a/.github/workflows/cron.yml
+++ b/.github/workflows/cron.yml
@@ -62,7 +62,7 @@ jobs:
     if: github.repository == 'Project-MONAI/MONAI'
     strategy:
       matrix:
-        container: ["pytorch:21.02", "pytorch:21.12"]  # 21.02 for backward comp.
+        container: ["pytorch:21.02", "pytorch:22.01"]  # 21.02 for backward comp.
     container:
       image: nvcr.io/nvidia/${{ matrix.container }}-py3  # testing with the latest pytorch base image
       options: "--gpus all"
@@ -106,7 +106,7 @@ jobs:
     if: github.repository == 'Project-MONAI/MONAI'
     strategy:
       matrix:
-        container: ["pytorch:21.02", "pytorch:21.12"]  # 21.02 for backward comp.
+        container: ["pytorch:21.02", "pytorch:22.01"]  # 21.02 for backward comp.
     container:
       image: nvcr.io/nvidia/${{ matrix.container }}-py3  # testing with the latest pytorch base image
       options: "--gpus all"
diff --git a/.github/workflows/pythonapp-gpu.yml b/.github/workflows/pythonapp-gpu.yml
index 7825c03ae1..635d5ab834 100644
--- a/.github/workflows/pythonapp-gpu.yml
+++ b/.github/workflows/pythonapp-gpu.yml
@@ -23,7 +23,7 @@ jobs:
           - "PT18+CUDA102"
           - "PT18+CUDA112"
           - "PT19+CUDA114"
-          - "PT110+CUDA115"
+          - "PT110+CUDA116"
           - "PT110+CUDA102"
         include:
           # https://docs.nvidia.com/deeplearning/frameworks/pytorch-release-notes
@@ -43,11 +43,11 @@ jobs:
             # 21.10: 1.10.0a0+0aef44c
             pytorch: "-h"
             base: "nvcr.io/nvidia/pytorch:21.10-py3"
-          - environment: PT110+CUDA115
+          - environment: PT110+CUDA116
             # we explicitly set pytorch to -h to avoid pip install error
-            # 21.12: 1.11.0a0+b6df043
+            # 22.01: 1.11.0a0+bfe5ad2
             pytorch: "-h"
-            base: "nvcr.io/nvidia/pytorch:21.12-py3"
+            base: "nvcr.io/nvidia/pytorch:22.01-py3"
           - environment: PT110+CUDA102
             pytorch: "torch==1.10.1 torchvision==0.11.2"
             base: "nvcr.io/nvidia/cuda:10.2-devel-ubuntu18.04"
diff --git a/Dockerfile b/Dockerfile
index 43dc103e0f..ab79eaaa5e 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -11,7 +11,7 @@
 
 # To build with a different base image
 # please run `docker build` using the `--build-arg PYTORCH_IMAGE=...` flag.
-ARG PYTORCH_IMAGE=nvcr.io/nvidia/pytorch:21.12-py3
+ARG PYTORCH_IMAGE=nvcr.io/nvidia/pytorch:22.01-py3
 FROM ${PYTORCH_IMAGE}
 
 LABEL maintainer="monai.contact@gmail.com"