diff --git a/global.json b/global.json
index bac6ff0124..853a36a25a 100644
--- a/global.json
+++ b/global.json
@@ -1,11 +1,11 @@
 {
   "sdk": {
-    "version": "5.0.301",
+    "version": "6.0.300",
     "rollForward": "latestMinor",
     "allowPrerelease": false
   },
   "msbuild-sdks": {
-    "MSBuild.Sdk.Extras": "3.0.38",
-    "Microsoft.Build.CentralPackageVersions": "2.0.79"
+    "MSBuild.Sdk.Extras": "3.0.44",
+    "Microsoft.Build.CentralPackageVersions": "2.1.3"
   }
 }
diff --git a/src/Prism.Core/Prism.Core.csproj b/src/Prism.Core/Prism.Core.csproj
index 34b64b1ca1..6ba4391fbd 100644
--- a/src/Prism.Core/Prism.Core.csproj
+++ b/src/Prism.Core/Prism.Core.csproj
@@ -1,7 +1,7 @@
 <Project Sdk="Microsoft.NET.Sdk">
 
   <PropertyGroup>
-    <TargetFrameworks>netstandard2.0;net461;net47;net5.0</TargetFrameworks>
+    <TargetFrameworks>netstandard2.0;net461;net47;net6.0</TargetFrameworks>
     <AssemblyName>Prism</AssemblyName>
     <PackageId>Prism.Core</PackageId>
     <RootNamespace>Prism</RootNamespace>
diff --git a/src/Uno/Prism.DryIoc.Uno/Prism.DryIoc.Uno.WinUI.csproj b/src/Uno/Prism.DryIoc.Uno/Prism.DryIoc.Uno.WinUI.csproj
index 7fd4f95fdd..361270404d 100644
--- a/src/Uno/Prism.DryIoc.Uno/Prism.DryIoc.Uno.WinUI.csproj
+++ b/src/Uno/Prism.DryIoc.Uno/Prism.DryIoc.Uno.WinUI.csproj
@@ -2,7 +2,7 @@
 <Project Sdk="MSBuild.Sdk.Extras">
   <PropertyGroup>
     <TargetFrameworks>netstandard2.0;xamarinios10;MonoAndroid11.0;MonoAndroid12.0;xamarinmac20</TargetFrameworks>
-    <TargetFrameworks Condition=" '$(OS)' == 'Windows_NT' ">$(TargetFrameworks);net5.0-windows10.0.18362</TargetFrameworks>
+    <TargetFrameworks Condition=" '$(OS)' == 'Windows_NT' ">$(TargetFrameworks);net6.0-windows10.0.18362</TargetFrameworks>
     <NoWarn>$(NoWarn);1591</NoWarn>
     <AssemblyName>Prism.DryIoc.Uno</AssemblyName>
     <PackageId>Prism.DryIoc.Uno.WinUI</PackageId>
@@ -19,7 +19,7 @@
 Prism provides an implementation of a collection of design patterns that are helpful in writing well structured and maintainable XAML applications, including MVVM, dependency injection, commanding, event aggregation, and more. Prism's core functionality is a shared library targeting the .NET Framework and .NET Standard. Features that need to be platform specific are implemented in the respective libraries for the target platform (WPF, Uno Platform, and Xamarin Forms). Prism for Uno Platform helps you more easily design and build rich, flexible, and easy to maintain Windows UWP, WinUI &amp; cross platform Uno applications.</Description>
     <PackageTags>prism;winui;windows;uno;mvvm;uwp;ios;android;macos;webassembly;linux;xaml;dryioc</PackageTags>
   </PropertyGroup>
-  
+
   <ItemGroup Condition="$(TargetFramework.StartsWith('xamarinios')) or $(TargetFramework.StartsWith('xamarinmac')) or $(TargetFramework.StartsWith('MonoAndroid')) or $(TargetFramework.StartsWith('netstandard'))">
     <PackageReference Include="Uno.WinUI" />
   </ItemGroup>
@@ -27,18 +27,18 @@ Prism provides an implementation of a collection of design patterns that are hel
   <PropertyGroup Condition="'$(TargetFramework)'=='netstandard2.0'">
     <DefineConstants>$(DefineConstants);__WASM__</DefineConstants>
   </PropertyGroup>
-  
+
   <ItemGroup>
     <Page Include="**\*.xaml" Exclude="bin\**\*.xaml;obj\**\*.xaml" />
     <Compile Update="**\*.xaml.cs">
       <DependentUpon>%(Filename)</DependentUpon>
     </Compile>
   </ItemGroup>
-  
+
   <ItemGroup>
     <UpToDateCheckInput Include="**\*.xaml" Exclude="bin\**\*.xaml;obj\**\*.xaml" />
   </ItemGroup>
-  
+
   <ItemGroup>
     <Compile Include="..\..\Wpf\Prism.DryIoc.Wpf\**\*.cs" Exclude="..\..\Wpf\Prism.DryIoc.Wpf\bin\**\*.cs;..\..\Wpf\Prism.DryIoc.Wpf\obj\**\*.cs" />
     <EmbeddedResource Include="..\..\Wpf\Prism.Unity.Wpf\Properties\**\*.resx" Link="Properties\%(FileName)%(Extension)" />
@@ -61,4 +61,4 @@ Prism provides an implementation of a collection of design patterns that are hel
     </EmbeddedResource>
   </ItemGroup>
   <Import Project="..\..\Containers\Prism.DryIoc.Shared\Prism.DryIoc.Shared.projitems" Label="Shared" />
-</Project>
\ No newline at end of file
+</Project>
diff --git a/src/Uno/Prism.Uno/Prism.Uno.WinUI.csproj b/src/Uno/Prism.Uno/Prism.Uno.WinUI.csproj
index 65e5d8f6a7..c13427b0f7 100644
--- a/src/Uno/Prism.Uno/Prism.Uno.WinUI.csproj
+++ b/src/Uno/Prism.Uno/Prism.Uno.WinUI.csproj
@@ -2,7 +2,7 @@
 <Project Sdk="MSBuild.Sdk.Extras">
   <PropertyGroup>
     <TargetFrameworks>netstandard2.0;xamarinios10;MonoAndroid11.0;MonoAndroid12.0;xamarinmac20</TargetFrameworks>
-    <TargetFrameworks Condition=" '$(OS)' == 'Windows_NT' ">$(TargetFrameworks);net5.0-windows10.0.18362</TargetFrameworks>
+    <TargetFrameworks Condition=" '$(OS)' == 'Windows_NT' ">$(TargetFrameworks);net6.0-windows10.0.18362</TargetFrameworks>
     <GenerateLibraryLayout>true</GenerateLibraryLayout>
     <AssemblyName>Prism.Uno</AssemblyName>
     <RootNamespace>Prism</RootNamespace>
diff --git a/src/Wpf/Prism.DryIoc.Wpf/Prism.DryIoc.Wpf.csproj b/src/Wpf/Prism.DryIoc.Wpf/Prism.DryIoc.Wpf.csproj
index 083e3d2fc7..f259a72ab3 100644
--- a/src/Wpf/Prism.DryIoc.Wpf/Prism.DryIoc.Wpf.csproj
+++ b/src/Wpf/Prism.DryIoc.Wpf/Prism.DryIoc.Wpf.csproj
@@ -2,7 +2,7 @@
 <Project Sdk="Microsoft.NET.Sdk.WindowsDesktop">
 
   <PropertyGroup>
-    <TargetFrameworks>net461;net47;netcoreapp3.1;net5.0-windows</TargetFrameworks>
+    <TargetFrameworks>net461;net47;net6.0-windows</TargetFrameworks>
     <UseWPF>true</UseWPF>
     <RootNamespace>Prism.DryIoc</RootNamespace>
     <PackageId>Prism.DryIoc</PackageId>
diff --git a/src/Wpf/Prism.Unity.Wpf/Prism.Unity.Wpf.csproj b/src/Wpf/Prism.Unity.Wpf/Prism.Unity.Wpf.csproj
index 142b7f7728..558166be04 100644
--- a/src/Wpf/Prism.Unity.Wpf/Prism.Unity.Wpf.csproj
+++ b/src/Wpf/Prism.Unity.Wpf/Prism.Unity.Wpf.csproj
@@ -2,7 +2,7 @@
 <Project Sdk="Microsoft.NET.Sdk.WindowsDesktop">
 
   <PropertyGroup>
-    <TargetFrameworks>net461;net47;netcoreapp3.1;net5.0-windows</TargetFrameworks>
+    <TargetFrameworks>net461;net47;net6.0-windows</TargetFrameworks>
     <UseWPF>true</UseWPF>
     <RootNamespace>Prism.Unity</RootNamespace>
     <PackageId>Prism.Unity</PackageId>
diff --git a/src/Wpf/Prism.Wpf/Prism.Wpf.csproj b/src/Wpf/Prism.Wpf/Prism.Wpf.csproj
index e7467a011b..99c14bee92 100644
--- a/src/Wpf/Prism.Wpf/Prism.Wpf.csproj
+++ b/src/Wpf/Prism.Wpf/Prism.Wpf.csproj
@@ -4,7 +4,7 @@
   <PropertyGroup>
     <AppDesignerFolder>Properties</AppDesignerFolder>
     <RootNamespace>Prism</RootNamespace>
-    <TargetFrameworks>net461;net47;netcoreapp3.1;net5.0-windows</TargetFrameworks>
+    <TargetFrameworks>net461;net47;net6.0-windows</TargetFrameworks>
     <UseWPF>true</UseWPF>
     <!--<Summary>Prism libraries related to user interface composition, regions, and modularity for WPF.</Summary>-->
     <Description>Prism is a fully open source version of the Prism guidance originally produced by Microsoft Patterns &amp; Practices. Prism provides an implementation of a collection of design patterns that are helpful in writing well structured, maintainable, and testable XAML applications, including MVVM, dependency injection, commanding, event aggregation, and more. Prism's core functionality is a shared library targeting the .NET Framework and .NET Standard. Features that need to be platform specific are implemented in the respective libraries for the target platform (WPF, Uno Platform, and Xamarin Forms).